Monday

We found that adding vitamin D

"We found that adding vitamin D substantially reduced the production of the protein driving the allergic response and also increased production of the protein that promotes tolerance," said Dr. Kolls, who also is professor and chair of genetics at LSU Health Sciences Center New Orleans. "Based on our results, we have strong rationale for a clinical trial of vitamin D to determine whether it can prevent or treat ABPA in patients with cystic fibrosis."

Cystic fibrosis is an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the United States (70,000 worldwide), according to the Cystic Fibrosis Foundation. A defective gene and its protein product cause the body to produce unusually thick, sticky mucus that clogs the lungs and leads to life-threatening lung infections and obstructs the pancreas and stops natural enzymes from helping the body break down and absorb food.

"These important findings by Dr. Kolls' team add to the growing body of evidence showing that vitamin D may play a critical role on immune responses and allergic diseases," said Juan Celedon, M.D., Dr.P.H., chief of the Division of Pulmonary Medicine, Allergy and Immunology at Children's Hospital.

Sunday

Hay feve begins around the middle of August

Ragweed allergy season can be even more miserable for those with dog, cat or dust mite allergies, according to new research. These year-round allergies appear to "pre-prime" the immune system so symptoms hit harder, according to a study recently published in the Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

Hay fever (known as seasonal allergic rhinitis) begins around the middle of August, when ragweed blooms. The typical symptoms sneezing, itching, stuffy nose and watery eyes can make sufferers miserable. Hay fever sufferers who also are allergic to cats, dogs or dust mites develop symptoms faster and (early on) more severely, the research suggests. Treating the cat, dog or dust mite allergy year round may help make the hay fever more manageable.

"People with hay fever react differently when ragweed allergy season arrives. Some start sneezing right away, and others don't, so we wanted to determine what makes certain people develop symptoms more quickly," said allergist Anne K. Ellis, MD, lead author of the study and an ACAAI member. "We tested a number of common perennial allergens and found that having an allergy to cats, dogs or dust mites sets hay fever sufferers up for faster onset of symptoms when exposed to ragweed."

The study included 123 people allergic to ragweed. Of those, 66 percent tested positive for cat allergies, 63 percent tested positive for dog allergies and 73 percent tested positive for dust mite allergies. All were exposed to ragweed for three hours in a special controlled room called the Environmental Exposure Unit (at Kingston General Hospital, Ontario), and completed symptom questionnaires every 30 minutes during exposure.

"On average, those who tested positive for cat, dog or dust mite allergies developed symptoms either faster than, or to a greater degree than those who tested negative for those allergies," said Dr. Ellis. "The differences seen at 90 minutes of exposure were less dramatic after 3 hours of exposure, however. That suggests that once the hay fever season is in full swing, the symptom differences between those with cat, dog or dust mite allergies and those without no longer exist."

To avoid the more intense early reaction, people with cat, dog and dust mite allergies should try to limit their exposure to those allergens before ragweed season starts, said Dr. Ellis. Because that often is not practical when it comes to family pets, an alternative is to treat their cat, dog or dust-mite allergies, she said.

"Allergy immunizations or year-round allergy medication can provide hay fever relief to those sufferers who have ongoing symptoms from cats, dogs or dust mites, even if they think the symptoms are mild and easily tolerated," said Neil Kao, MD, chair of the ACAAI Rhinitis/Sinusitis Committee. "They'll likely find ragweed allergy season easier to endure if they're treating their perennial allergies."

Those who suspect they have hay fever or other allergies should get tested by an allergist a doctor who is expert in diagnosing and treating allergies and asthma.

Friday

Can Turmeric (Curcumin) Help Prevent Cancer?

Can Turmeric (Curcumin) Help Prevent Cancer?
Turmeric is a spice derived that is a member of the ginger family.
Curcumin is the principal polyphenolic compound in turmeric and is by
itself an antioxidant and also supports the production of glutathione,
another key antioxidant during times of need. In recent years researchers
has revealed that turmeric can play a role in the prevention of cancer
formation.

Wednesday

Can Eating More Broccoli and Cauliflower Reduce the Risk of Cancer?

Can Eating More Broccoli and Cauliflower Reduce the Risk
of Cancer?
There is good reason to include cruciferous (or Brassica) vegetables in
your diet arsenal to support cancer prevention. These vegetables include
broccoli, Brussels sprouts, cabbage, cauliflower, collard greens, arugula,
kale, kohlrabi, mustard, rutabaga, turnips, bok choy, Chinese cabbage,
wasabi, horse radish, radish, and watercress. In addition to key anti-
oxidant vitamins and minerals, cruciferous vegetables are rich sources of
glucosinolates, which are the sulfur-containing compounds responsible
for their pungent aromas and unique taste. Routine preparation of these
vegetables by chopping as well as chewing leads to the breakdown of
glucosinolates which in turn give rise to indoles and isothiocyanates
which seem to help prevent cancer.
   Broccoli and cauliflower contain sulfur-based nutrients that can
   help defend against cancer.


Sunday

It is truly remarkable what our bodies

        The Very Basics of Humans
        and the World We Inhabit
Have you ever stopped and wondered why we (humans) are as we are,
and why we do what we do? It is truly remarkable what our bodies are
capable of doing and how our bodies operate to perform various tasks.
Yet, we are just one of millions of different species inhabiting this planet,
all with a unique story to tell. And, like our fellow planet-mates, we must
abide by the basic objectives of life, namely to function as an independent
being (self-operate), defend ourselves both externally and internally,
nourish ourselves, and of course to reproduce, which is without question
the ultimate objective of all life-forms.
   Yet, we are special in that we have a relatively large brain and the intel-
lectual capacity to try to understand ourselves and, in accordance, how we
are to be nourished. In this chapter we will begin to explore the very basis
of our being and the world we live in. This will begin to set the stage for
understanding what it will take to nourish our body for optimal health and
longevity. We will answer questions about basic concepts such as elements,
atoms, molecules, oxidation, chemical reactions, water solubility, and
acids and bases. If you have a science background this site might seem
too rudimentary and you might consider moving on to the next ....

Wednesday

More importantly

What, you may ask, is a public relations man doing writing a site on nature cure ? The answer
is simple : good health ought to be everybody's concern, not solely the medical profession's
business. More importantly, in my own case, I suffered immen- sely, for many years, largely due
to the shortcomings of the modern medical system. In my despair, I earnestly began my study of
natural methods of treatment and cure of disease, as also the ways and means of maintaining
good health. Putting the time-tested nature cure methods into practice proved so beneficial in my
own case, that I took to studying their application for several other diseases as well. What began
as mere jottings was gradually expanded into full-length articles on the subject " Cure Without
Drugs ", several of which were published in "The Economic Times. " The readers' response to
the series was overwhelming and several of them suggested that the articles be complied in
book form, to benefit more people. "Health the Natural Way " was the result. This book as well
as my second book titled " Diet Cure For Common Ailments " published three years laters, was
well received by the press and the public. This fact coupled with the immense popularity of my
articles on health, nutrition and nature cure being published in several leading newspapers and
magazines, have prompted me to write a comprehensive book on nature cure under the present
title for the benefit of the general public.

Where nutrition is concerned

Most members of the "medical" profession do not want to know. They do realise their patients are not losing weight, but they put it down to cheating and secret binges. Some slimming professionals even run group therapy sessions, at which members are applauded when they are able to show they have lost weight and made to feel ashamed of any gain.1 The mental cruelty involved in these practices is positively mediaeval. Moreover, stipulating a 1500 calorie diet without detailing what it is to contain is quite inadequate. It simply serves to focus on the energy value of foods without taking account of their nutritional value.


Apart from a few specialists, doctors tend to be disinclined to update their understanding of these matters and are usually not knowledgeable about them in the first place. Where nutrition is concerned, they seem to have little scientific understanding going beyond the commonly held views.


What is more, it is not a field in which doctors in general are particularly interested. I have noticed that of the twenty or so I have worked with on this book, all of them, without exception, were originally led to research and experiment in the field because they themselves had a serious weight problem to solve.

Tuesday

Sugar-sweetened beverages



Sugar-sweetened beverages, a major source of fructose, raise serum uric acid levels and are associated with an increased risk of gout, hypertension, and diabetes. However, it is unclear whether the associations with hypertension and diabetes are caused by fructose per se, or through some other mechanism. Nevertheless, given their demonstrated adverse health associations and the lack of any health benefit, the evidence favors minimization of sugar-sweetened beverage intake.
Herbal Products

Thistle for the treatment of liver diseases

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Silymarin and its major constituent, Silibinin, are extracts from the medicinal plant Silybum marianum (milk thistle) and have traditionally been used for the treatment of liver diseases. Recently, these orally active, flavonoid agents have also been shown to exert significant anti-neoplastic effects in a variety of in vitro and in vivo cancer models, including skin, breast, lung, colon, bladder, prostate and kidney carcinomas. The aim of the present review is to examine the pharmacokinetics, mechanisms, effectiveness and adverse effects of silibinin's anti-cancer actions reported to date in pre-clinical and clinical trials. The review will also discuss the results of current research efforts seeking to determine the extent to which the effectiveness of silibinin as an adjunct cancer treatment is influenced by such factors as histologic subtype, hormonal status, stromal interactions and drug metabolising gene polymorphisms. The results of these studies may help to more precisely target and dose silibinin therapy to optimise clinical outcomes for oncology patients.

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How useful condoms are in preventing herpes

Practicing safe sex is one of the best preventative health measures a person can take, and the best form of safe sex, outside of abstinence, is the condom. Not only do condoms safeguard against unwanted pregnancies, they also protect against infection from various sexually transmitted diseases (STDs), such as HIV, gonorrhea, Chlamydia and trichomoniasis; discharge diseases that are transmitted through infected semen or vaginal fluids. However, researchers say condoms provide a lesser degree of protection against the spread of another STD—genital herpes—because it can be transmitted through contact with infected skin that isn't covered or protected by the condom, but the exact protective effect has remained unclear. To get a more definitive idea of how useful condoms are in preventing herpes, researchers at the University of Washington analyzed data on a total of 5,384 people; two-thirds of whom were male, 94 percent were heterosexual. All study participants were free of infection when the studies began, but over a follow-up period of 12 to 19 months, 415 became infected with the herpes simplex virus 2 (HSV-2), the virus that most often causes genital herpes. For those who reported using a condom 100 percent of the time, the risk of contracting the virus was found to be 30 percent less than those who did not use condoms. "Although the magnitude of the protective effect was not as large as has been observed with other STIs, a 30 percent reduction in HSV-2 incidence can have a substantial benefit for individuals as well as a public health impact at the population level," said lead author Dr. Emily T. Martin of Children's Hospital Research Institute at the University. "Thirty percent is partial protection, but its protection." The researchers said the risk of being infected was reduced 7 percent "every additional 25 percent of the time condoms were used during anal or vaginal sex" and increased with the frequency of unprotected sex. There was no significant difference in condom effectiveness between genders. "It's the consistent use of the condom that's important," Martin said. "If you don't know the STD status of your partner, a condom is always a good idea." Dr. Jeffrey D. Klausner, director of STD Prevention and Control Services at the San Francisco Department of Public Health, said the study provides more scientific evidence that condoms work. "We know condoms can prevent the spread of sexually transmitted infections like HIV, herpes, warts, hepatitis, gonorrhea, Chlamydia and syphilis, but it's always been hard to show that in research studies," he said. "If condoms can hold air and water, I never understood why folks thought they would not prevent the spread of germs, which are much, much larger than air or water molecules." Klausner added that these findings should help in efforts to get condoms into the hands of sexually active adults and teens. As many as 50 million Americans—about one in five adults—are infected with the genital herpes virus, with about one million new infections each year. As many as 80-90 percent of those infected fail to recognize herpes symptoms or have no symptoms at all. People with herpes may spread the disease even though they don't realize they have an infection or while their disease appears to be inactive and no sores can be seen. Herpes is a lifelong disease with no cure, but antiviral drugs can partially control the duration and severity of episodes.

Monday

Botanical medicine.

Plants have been used as medicine since the dawn of human civilization. Also called "botanical medicine" or "phytomedicine," herbal medicine uses all the parts of various plants for healing: seeds, berries, leaves, roots, bard, flowers. The World Health Organization reports that 80 percent of people worldwide use herbal medicine. In 1998, Americans alone spent over $4 billion on herbal products.

Over 700,000 different plants have been identified, but many more grow in isolated and remote environments, like the Amazon jungle. We have scientific data about only a handful, but even these have proven very useful as many modern pharmaceutical drugs are derived from plants. For instance, digitalis, from the foxglove plant, has been used by herbalists to treat heart disease. Extracts from this plant and its compounds are used in modern heart medications. The herb ephedra has been used in Chinese Medicine for over 2,000 years to treat asthma. The extract, Ephedrine, is used in commercial asthma medications

Though the United States Food and Drug Administration (FDA) does not recognize licenses of drugs from overseas, research in other countries has brought many medicinal plants into modern usage in Europe. Germany utilizes over 600 plants in medicines available by prescription. These plant-medicines are prescribed by over two-thirds of German doctors.

History
Healing with plants has been mentioned as far back as man has been keeping records. Ancient Egyptian papyrus relate recipes for cures using plants, as do medical systems from other cultures, such as Ayurveda in India and Traditional Chinese Medicine. With the advent of modern chemistry, scientists began to analyze the chemical make-up of various plants, and then synthesized compounds for use in pharmaceuticals and medicine. The FDA now classifies many herbs as dietary supplements, since the U.S. Dietary Supplement Health and Education Act (DSHEA) of 1994. Most herbs are sold over-the-counter, that is, without a prescription, and registration as a dietary supplement does not regulate the manufacture of herbal medicine.

Usage
Herbs can be taken internally as tea, tinctures, or extracts. They can also be added to oils or creams and used externally, not only for the hair or skin, but for absorption through the skin to treat various ailments.

Some of the more commonly used herbs in the United States are echinacea, used to boost immunity, and ginkgo bilboa, used for memory retention. Commonly utilized teas include chamomile and peppermint. Food plants such as ginger, chocolate, flax seed oil, and garlic are also classified in herbal medicine because of their healing qualities.

Side Effects from Herbal Medicine
Some herbal remedies do have side effects or allergic reactions, so it is important to talk over health concern with your doctor or health provider before beginning any new therapy. A study in the New England Journal of Medicine suggested that over half of people using herbal medicines did not report the usage to their doctors, and this can interfere with other drugs or medical treatments. You can research warnings and safety advice at the FDA website  or the National Center for Complementary and Alternative Medicine.



Integrating natural and conventional treatments is often the most beneficial path to health, as one third of Americans know, so keeping our health providers informed will only speed the integration of herbal medicine into its rightful place as a healing agent

Saturday

Fibromyalgia is notoriously difficult to treat


Fibromyalgia is notoriously difficult to treat. Medication tends to reduce muscle pain, fatigue, and other symptoms of the chronic condition by just 30% to 50%. As a result, many patients turn to diet and lifestyle changes for added relief. Learning which foods to avoid is a good place to start, since fibro patients often have food sensitivities that may not show up in food allergy tests. In one survey, 42% reported that certain foods made their pain and stiffness worse.

Friday

pharmaceutical ingredient


"Herbal Diet Natural" contains an undeclared pharmaceutical ingredient similar to the prescription drug sibutramine. Sibutramine may pose serious health risks, particularly to people with heart problems. Consumers who have purchased "Herbal Diet Natural" are advised to consult with a medical professional if they have used the product or have concerns about their health, says Health Canada.

Sibutramine is a prescription drug used to treat obesity.  The use of sibutramine may cause serious side-effects, including cardiovascular reactions, such as increased blood pressure, chest pain, and stroke, in addition to dry mouth, difficulty sleeping and constipation. Sibutramine should only be used under the supervision of a healthcare practitioner. Sibutramine should not be taken by people who have had a heart attack, coronary artery disease, heart-related chest pain, irregular heart beats, congestive heart failure, a stroke or symptoms of a stroke, in individuals with unstable or poorly controlled high blood pressure, or in patients who have clinically diagnosed depression or have a psychiatric illness. Sibutramine is not recommended for women who are pregnant, breastfeeding or planning to become pregnant.

According to the product label, Herbal Diet Natural also contains glucomannan used for the treatment of weight loss. In January 2010, Health Canada advised Canadians that natural health products containing the ingredient glucomannan in tablet, capsule or powder form, which are currently on the Canadian market, have a potential for harm if taken without at least 8 ounces of water or other fluid. The risk to Canadians includes choking and/or blockage of the throat, esophagus or intestine. These products should NOT be taken immediately before going to bed.

Wednesday

Cranberry prevents bacteria from sticking to the bladder wall long enough to cause an infection

Cranberry for Urinary-Tract Infection

Cranberry prevents bacteria from sticking to the bladder wall long enough to cause an infection. Finnish researchers divided 150 recurrent UTI sufferers into three groups. One drank cranberry juice (50 milliliters a day). Another took Lactobacillus. The third took nothing. After six months, 36 percent of the no-treatment group and 39 percent of the Lactobacillus group reported at least one recurrence. Of the juice drinkers, only 16 percent had recurrences. Other options are dried cranberries (Craisins) and cranberry-extract capsules. "I recommend cranberry for UTI," Duke says. "But if you drink the juice, you have to drink a lot. It's usually easier to munch on the dried berries or take capsules."


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Tuesday

VITAMIN B1 (Thiamine) Promotes growth

Buy Vitamin B Complex<

Buy Vitamin B Complex

VITAMIN B1 (Thiamine) Promotes growth, improves mental attitude, aids digestion, helps strengthen nervous system and prevent stress. HERBAL SOURCES: Alfalfa, bladder wrack, burdock root, catnip, cayenne, chamomile, chickweed, eyebright, fennel seed, fenugreek, hops, nettle, oat straw, parsley, peppermint, raspberry leaves, red clover, rose hips, sage, yarrow, and yellow dock.

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Saturday

Synonyms Echinacea

Synonyms Echinacea

Alkamides, American coneflower, Asteraceae (family), black Sampson, black Susan, cichoric acid, cock-up-hat, combflower, coneflower,  Echinacea angustifolia ,  Echinacea pallida , Echinacea Plus,  Echinacea purpurea , Echinacin®, Echinacin® EC31, Echinaforce®, Echinaforce® Forte, Echinaguard®, Echinilin® (Factors R & D Technologies, Burnaby, British Columbia, Canada), hedgehog, igelkopf, Indian head, Kansas snake root, kegelblume, narrow-leaved purple coneflower, Pascotox®, polysaccharides, purple coneflower, red sunflower, rudbeckia, SB-TOX, scurvy root, snakeroot, solhat, sun hat.

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Study 2010 stop smoke

A new study shows that smokers who quit have healthier arteries a year later and probably will have less risk of heart disease as a result.

Doctors say the improvement came even though people who kicked the habit gained an average of 9 pounds. The study at the University of Wisconsin in Madison involved 1,500 smokers who were given one of five methods, such as nicotine patches or lozenges, to help them quit.

About one-third were successful, regardless of which method they used. Ultrasound tests were used to measure the health of their arteries before and after the study.

Results were reported Monday at a cardiology conference in Atlanta.

Stronger placebo effect


Like massage, acupuncture is difficult to study because it's hard to give a "fake" massage or "placebo" acupuncture. Says Clauw: "In 'sham' or placebo controlled trials in chronic pain, more studies have shown that acupuncture doesn't work. But that doesn't necessarily mean that it's not effective—it might be that there really is no such thing as sham acupuncture. Acupuncture might somehow be effective in engendering a placebo response." Whether that matters if someone feels significant pain relief is a question only the patient can answer. "The best evidence that it's effective is that a lot people will pay out of pocket to use it," he says.
Clauw himself conducted a fascinating imaging study of acupuncture, finding that while patients with fibromyalgia reported decreased pain with both fake and real acupuncture, fake acupuncture affected brain opioid receptors in a way that was more comparable to that seen with placebo. "Sham acupuncture may work via placebo effects and active acupuncture may work by more specific effects. That could help explain why trials don't show much difference," he says.
Some have claimed that electroacupuncture—which runs a small current through acupuncture needles—is more effective than needles alone, but Clauw says it's even harder to parse out placebo effects here. "It may give a stronger placebo effect," he says. For people in pain, however, that could be a good thing.

related pain relief:


Friday

Cafergot tablets buy

`
`

Cafergot tablets buy
Ergotamine/caffeine (Rectal)
Caffeine (KAF-een), Ergotamine (er-GOT-a-meen)
Treats or prevents migraine and cluster headaches.
Brand Name(s):
Cafergot,Migergot
There may be other brand names for this medicine.
When Cafergot Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to ergotamine or caffeine, or if you are pregnant or plan to become pregnant. You should not use this medicine if you have high blood pressure, kidney disease, liver disease, heart disease, blood vessel disorders, or problems with circulation.
How to Use Cafergot:
Suppository
Your doctor will tell you how much of this medicine(Cafergot) to use and how often. Do not use more medicine or use it more often than your doctor tells you to. Never take rectal suppositories by mouth.
Wash your hands with soap and water before using Cafergot. Remove the foil or wrapper from the suppository before inserting it.
To make the suppository easier to insert, you may use a lubricating gel such as K-Y® Jelly, but do not use petroleum jelly (Vaseline®).
Lie on your left side with your left leg straight or slightly bent, and your right knee bent upward. Gently push the pointed end of the suppository into the rectum about 1 inch.
Keep lying down for about 15 minutes to keep the suppository from coming out before it melts. Then, wash your hands again.
How to Store and Dispose of Cafergot:
Store Cafergot at room temperature, away from heat and direct light. Follow the directions on the medicine package label about storing the suppositories in the refrigerator, but do not freeze them.
Keep all medicine out of the reach of children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using dopamine (Intropin®), sibutramine (Meridia®), antibiotics (such as Biaxin®, Dynabac®, Ery-Tab®), blood pressure medicine (such as atenolol, metoprolol, Inderal®, Toprol®), medicines to treat HIV/AIDS (Agenerase®, Crixivan®, Invirase®, Norvir®, Rescriptor®, Sustiva®, Viracept®), or other medicines to treat migraine headaches (Amerge®, Imitrex®, Maxalt®, Zomig?).
Do not drink alcohol while you are using this medicine. Avoid caffeine (coffee, tea, soft drinks, chocolate).
Smoking may make your headaches worse or increase the side effects of this medicine.
Warnings While Using This Medicine:
Make sure your doctor knows if you are breastfeeding, or if you have a stomach ulcer, glaucoma, or history of a stroke.
If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
Possible Side Effects While Using Cafergot:
Call your doctor right away if you notice any of these side effects:
Fast or slow heartbeat
Lightheadedness or fainting
Numbness or tingling in your fingers or toes
Pain or discomfort behind your breastbone
Pain, itching, or irritation around your rectum
Skin rash, swelling, or itching
Vomiting, numbness, tingling feeling, or pain and blue discoloration of your hands and feet
If you notice these less serious side effects, talk with your doctor:
Muscle pain
Nausea, vomiting, diarrhea, or stomach pain
Nervousness, irritability, dizziness
Weakness in your legs
If you notice other side effects that you think are caused by this medicine, tell your doctor.

Thursday

Bunch of grapes help to fight high blood pressure

Could eating a bunch of grapes help to fight high blood pressure related to a salty diet? Could they also calm other factors that are also related to heart diseases such as failure of the heart? You'd be amazed at what those oval rounds of goodness have packed inside their black, red or green skin.

A new study conducted by the University of Michigan Cardiovascular Center gives tantalizing clues to the potential of grapes in reducing the risk of cardiovascular complications. The effect is thought to be due to the high level of phytochemicals, which are naturally occurring antioxidants that grapes contain.

The current study was performed on laboratory rats. The researchers studied the effects that regular table grapes (a blend of black, green and red grapes) that were mixed into the rat diet in a powdered form, as part of either a diet low in salt or a diet high in salt. The researchers then performed many comparisons between the rats that were consuming the test diet and the control rats that were receiving no grape powder—including some that had received a mild dose of a common blood pressure medication. All of the rats were from a research breed that is prone to developing high blood pressure when they are fed a salty diet.

Mitchell Seymour, M.S., who lead the research as part of his doctoral work in nutrition science at the Michigan State University, said that in all, after 18 weeks, the rats that had received the diet with the grape-powder had reduced inflammation in their bodies, lower blood pressure, better heart function, and fewer signs of heart muscle damage that the rats that had eaten the same salty diet but did not receive any grapes. The rats that received the blood pressure pill, hydrazine, along with the salty diet also had lower blood pressure, but their hearts were not protected from damage as the rats in the grape-fed group. "These findings support out theory that something within the grapes themselves has a direct impact on cardiovascular risk, beyond the simple blood pressure-lowering impact that we already know can come from a diet rich in fruits and vegetables."

Steve Bolling, M.D., who is a professor of cardiac surgery at the U-M Medical School, notes that the rats in the study were in a put in a similar situation as millions of Americans, who have suffered from high blood pressure related to their diet, and who develop heart failure over time because of the prolonged hypertension. He also stated that the inevitable downhill sequence from hypertension to heart failure was changed by adding the grape powder to a high salt diet. Bolling explained, " Although there are many natural compounds in the grape powder itself that may have an effect, the things that we think are having an effect against the hypertension may be the flavanoids—either by direct antioxidant effects, by indirect effects on cell function, or both. These flavanoids are rich in all parts of the grape—skin, flesh, seed, all of which were in our powder."

Although the current study  was supported in part by the California Table Grape Commission, which also supplied the researchers with the grape powder, the authors note that the commission played no role in the design of the study, analysis, conduct, or preparation of the journal article for publication. Seymour has also received funding from the National Heart, Lung, and Blood institute, which is part of the National Institutes of Health, through a National Research Science Award.

This does not mean it is time to tell patients to throw all of their medication away and just eat grapes. However, the research on the grapes and other fruits that contain high levels of antioxidant phytochemicals continues to show promise. So does the research on the impact of red wine on the heath of the heart, though that issue is also far from being settled.

Bolling suggested that if people wish to lower their blood pressure, reduce the risk of having heart failure, or help their weakened hearts retain as much pumping power as possible should follow tried-and-true advice: Cut down on the amount of salt that you get through your drink and food. "There is, as we know, a great variability, perhaps genetic even, in sensitivity to salt and causing hypertension. Some people are very sensitive to salt intake, some are only moderately so, and there are perhaps some people who are salt resistant. But in general we say stay away from excess salt."

He also notes that the popular DASH diet, which is low in salt and high in vegetables and fruits, has been proven to reduce mild high blood pressure without taking any medications. The dose of whole table grape powder that was consumed in the new study was roughly equivalent to a person eating nine human-sized servings of grapes daily. Currently, five to nine servings of vegetables and fruits are recommended as part of the Dash diet plan.

In all, the researchers say that this study demonstrates that a diet enriched with grapes can have broad effects on the development of hypertension and the risk factor that come along with it. Whether the effect can be replicated on humans, the researchers say, remains yet to be seen.


http://www.healthnews.com/nutrition-diet/grapes-newest-heart-healthy-food-2044.html

Tuesday

Globally more than 30 million people are infected with HIV

University of Michigan scientists have identified a new reservoir for hidden HIV-infected cells that can serve as a factory for new infections. The findings, which appear online March 7 in Nature Medicine, indicate a new target for curing the disease so those infected with the virus may someday no longer rely on AIDS drugs for a lifetime. "Antiviral drugs have been effective at keeping the virus at bay. However once the drug therapy is stopped, the virus comes back," says senior author of the study Kathleen L. Collins, MD, Ph.D., associate professor of both internal medicine and microbiology and immunology at the U-M Medical School. In people infected with HIV (human immunodeficiency virus), the virus that causes AIDS, there's an unsolved problem with current antiviral drugs. Though lifesaving, they cannot root the virus out of the body. Infected cells are able to live on, undetected by the immune system, and provide the machinery for the virus to reproduce and spread. Important new research by U-M has discovered that bone marrow, previously thought to be resistant to the virus, can contain latent forms of the infection. "This finding is important because it helps explain why it's hard to cure the disease," Collins says. "Ultimately to cure this disease, we're going to have to develop specific strategies aimed at targeting these latently infected cells." "Currently people have to take antiviral drugs for their entire life to control the infection," she says. "It would be easier to treat this disease in countries that don't have the same resources as we do with a course of therapy for a few months, or even years. But based on what we know now people have to stay on drugs for their entire life." Using tissue samples, U-M researchers detected HIV genomes in bone marrow isolated from people effectively treated with antiviral drugs for more than six months. While further studies are needed to demonstrate that stem cells can harbor the HIV virus, the study results confirm that HIV targets some long-lived progenitor cells, young cells that have not fully developed but mature into cells with special immune functions. When active infection occurs the toxic effects of the virus kill the cell even as the newly made viral particles spread the infection to new target cells. "Our finding that HIV infects these cells has clear ramifications for HIV disease because some of these cells may be long-lived and could carry latent HIV for extended periods of time," she says. "These HIV cell reservoirs can be induced to generate new infections." The new research gives a broader view of how HIV overwhelms the body's immune system and devastates its ability to regenerate itself. Globally more than 30 million people are infected with HIV, including millions of children. Improvements have been made since the 1990s in the way the disease is treated that has led to an 85 percent to 90 percent reduction in mortality. "Drugs now available are effective at treating the virus, making HIV more of a chronic disease than a death sentence," Collins says. "This has made a huge impact in quality of life, however only 40 percent of people worldwide are receiving anti-viral drugs and unfortunately that means that not everybody is benefiting."




http://www.hivplusmag.com/NewsStory.asp?id=21870&StoryDate=03/09/2010

Sunday

Fear of anthrax infection.People Want the Drug Cipro

Health and Human Services Secretary Tommy Thompson asked Americans not to buy and hoard the pharmaceuticals, although there is some controversy over whether the country has enough drugs on hand. Claude Allen, HHS deputy secretary, told the House Committee on Veterans Affairs that part of $1.5 billion the department has requested, would be used to increase the pharmaceutical stockpile of anthrax treatment. The $1 billion-a-year drug, manufactured by German drugmaker Bayer AG, has been used in the United States since 1987 to treat a variety of infections. The Food and Drug Administration approved it for anthrax treatment last year. Fear of anthrax infection has taken hold across the country and even in Europe where several recent scares have been reported. People Want the Drug Dr. Daisy Merey, who runs a family practice in West Palm Beach, said she prescribed Cipro for several people who wanted it around just in case they got sick. "A lot of people who are coming in for checkups are also asking about Cipro," Merey told Reuters. "We don't recommend taking antibiotics as a preventive measure because there are side effects. If people really want it just to have in case something happens, we'll prescribe it to them." One reason doctors don't like to have people procuring prescriptions for Cipro online is that it's a very strong antibiotic that is generally reserved for tough cases, said Dr. Nancy Snyderman on ABCNEWS' Good Morning America. "It's not even a first-line drug of choice for most infections," Snyderman said. "This is a kind of medication you use when other things fail." Since anthrax doesn't widely disperse itself, there is no need to stock up on Cipro, said Stephen Ostroff, chief epidemiologist at the Centers for Disease Control and Prevention in Atlanta. "And in all of the current situations that we're aware of, it's really mostly been confined to people who've had direct contact with these contaminated envelopes," Ostroff told Good Morning America.




Related antibiotics

Amoxicillin Trimox Adoxa Zithromax AUGMENTIN Bactrim Myambutol E-mycin

Saturday

Reduce the risks of high blood pressure and heart failure

Sticking with a healthy diet and lifestyle can reduce the risks of high blood pressure and heart failure, in which the heart cannot pump enough blood to supply the body with oxygen and nutrients, according to the findings of two studies in the Journal of the American Medical Association.

In the first investigation, Dr. Luc Djousse, from Harvard Medical School in Boston, and colleagues analyzed data from 20,900 men in the Physicians' Health Study I (1982-2008) to assess the link between lifestyle factors and the lifetime risk of heart failure. The subjects were followed for 22.4 years, on average.

The lifetime risk of heart failure, assessed at age 40 years, was about one in seven, the report indicates.

A variety of healthy lifestyle habits were linked to a lower risk of heart failure. These habits included maintaining a normal body weight , not smoking , regular exercise, moderate alcohol intake, consumption of breakfast cereals, and consumption of fruits and vegetables.

Men who adhered to none of the healthy lifestyle factors had the highest lifetime risk of heart failure-21.2 percent--while those who adhered to four or more had the lowest risk-10.1 percent.

The second investigation, conducted by Dr. John P. Forman and colleagues, from Harvard Medical School, Boston, involved an analysis of data from 83,882 women in the Nurses' Health Study (1991-2005). The goal was to assess the impact that various diet and lifestyle factors had, in combination, on the risk of high blood pressure.

The study focused on six factors, previously tied to a reduced risk of high blood pressure: normal body weight, vigorous exercise for an average of 30 minutes per day, consuming a healthy diet, modest alcohol intake, use of pain medications less than once per week, and use of supplemental folic acid, a form of vitamin B .

The presence of 6, 5, 4, and 3 of the factors cut the risk of high blood pressure by 78, 72, 58, and 54 percent, respectively, relative to the complete absence of these factors.

The factor with the single greatest impact on high blood pressure was body weight. Women who were obese were 4.7-times more likely to develop high blood pressure than were women of normal body weight.

The authors conclude that many new cases of high blood pressure could be prevented through adherence to the low-risk dietary and lifestyle factors described. This, they add, could yield major public health benefits.

SOURCE: Journal of the American Medical Association, July 22/29, 2009.